Subject(s)
Humans , Infant, Newborn , Polycystic Kidney, Autosomal Dominant/diagnosis , Polycystic Kidney, Autosomal Dominant/etiology , Polycystic Kidney, Autosomal Dominant/pathology , Polycystic Kidney, Autosomal Dominant , Polycystic Kidney, Autosomal Recessive/diagnosis , Polycystic Kidney, Autosomal Recessive/etiology , Polycystic Kidney, Autosomal Recessive/pathology , Polycystic Kidney, Autosomal Recessive , Diagnosis, Differential , Diagnostic Imaging , Polycystic Kidney Diseases/classification , Polycystic Kidney Diseases/genetics , Genetic CounselingABSTRACT
Many diseases can be associated with kidney cysts and they may be classified as hereditary and non-hereditary renal cystic disease. The first group can be sub-classified as autosomal recessive cystic disease, such as autosomal recessive polycystic kidney disease and nephronophthisis, as autosomal dominant kidney disease such as autosomal dominant polycystic kidney disease, glomerulocystic disease and tuberous sclerosis, and as cysts associated with syndromes. Cystic dysplasia, multicystic dysplastic kidney, simple cyst, multilocular cysts, Wilm's tumor and acquired cystic kidney disease are classified in the second group. The genetic study of renal cysts is becoming increasingly important, due to the possible therapeutic interventions that could be devised in the future. The aim of this review is to provide a fast and easy clinical approach to renal cystc.
Subject(s)
Humans , Kidney Diseases, Cystic , Diagnosis, Differential , Kidney Diseases, Cystic/classification , Kidney Diseases, Cystic/genetics , Multicystic Dysplastic Kidney/classification , Multicystic Dysplastic Kidney , Polycystic Kidney Diseases/classification , Polycystic Kidney Diseases/genetics , Polycystic Kidney Diseases , PrognosisABSTRACT
Este artigo foi dividido em duas partes. A primeira consiste em breve revisäo da classificaçäo e características clínicas e diagnósticas das doenças renais policísticas (DRP), principalmente nas suas formas hereditárias. A segunda parte é composta por uma revisäo atualizada da patogenia das doenças císticas renais, onde säo comentados os possíveis mecanismos e hipóteses para a formaçäo e expansäo dos cistos, com alguns diagramas pessoais elucidativos, incluindo a cistogênese da doença renal císitica adquirida (DRCA), uma vez que parece haver um denominador comum ou mecanismo unificador na formaçäo dos cistos em todas as formas de doenças císticas.